Chronic psychosis
Adult: As zuclopenthixol decanoate ester: Initially, a test dose of 100 mg deep IM into the upper buttock or lateral thigh to assess tolerance, followed after at least 1 week by 200-500 mg every 1-4 weeks, adjusted according to response. Injection volumes >2mL to be distributed between 2 injection sites. Max: 600 mg per week.
Elderly: Reduce dose to ¼ or ½ of usual initial dose.
Elderly: Reduce dose to ¼ or ½ of usual initial dose.
Intramuscular
Psychoses
Adult: As acetate: 50-150 mg via deep IM inj. May repeat, if needed, after 2-3 days. An additional dose 1-2 days after the 1st dose may be required in some patients. Not >4 inj should be given in a max course of 2 wk and total dose should not exceed 400 mg. Maintenance: May start oral zuclopenthixol HCl 2-3 days after the last acetate inj or begin IM inj of decanoate with the last inj of the acetate.
Elderly: As acetate ester: Dose reduction may be needed. Max: 100 mg/dose.
Elderly: As acetate ester: Dose reduction may be needed. Max: 100 mg/dose.
Oral
Psychoses
Adult: Initially, 20-30 mg daily in divided doses. Usual maintenance dose: 20-50 mg daily. Up to 150 mg daily for severe or resistant cases.