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Known hypersensitivity to Voriconazole or any ingredient in the formulation.
Concomitant use of carbamazepine, CYP3A4 substrate (terfenadine, astemizole, cisapride, pimozide, quinidine), efavirenz (400 mg/day or more), ergot alkaloids (ergotamine, dihydroergotamine), long acting barbiturates (phenobarbital, mephobarbital), rifabutin, rifampin, sirolimus, St John's Wort.
Concomitant use with high dose ritonavir (800 mg/day); also avoid low dose ritonavir (200 mg/day), unless potential benefits outweigh risks.
