Vaspril Dosage & Drug Information

Concise Prescribing Info

Contents

Ramipril

Indications/Uses

HTN & CHF. Prophylaxis of CV events in high-risk patients (MI, stroke). Delayed nephropathy occurring in non-diabetic & diabetic patients w/ HTN.

Dosage/Direction for Use

Adult HTN Initially 2.5 mg once daily. Maintenance: 2.5-5 mg daily as a single dose may increase up to 10 mg daily, if needed. Heart failure Initially 1.25 mg once daily. Max: 10 mg daily. Prophylaxis of CV events in high-risk patients Initially 2.5 mg once daily for 1 wk, then increased if tolerated to 5 mg once daily for 3 wk. Maintenance: 10 mg daily. Delayed nephropathy occurring in non-diabetic & diabetic patients w/ HTN Initially 1.25 mg once daily. Max: 5 mg daily.

Administration

May be taken with or without food.

Contraindications

Hypersensitivity to ACE inhibitors. Patients w/ angioedema history from ACE inhibitors, bilateral renal artery stenosis or a single kidney w/ unilateral renal artery stenosis. Aortic stenosis or outflow tract obstruction. Pregnancy & lactation.

Special Precautions

Cough; renal impairment; hyperkalaemia; angioneurotic oedema of face, lips, tongue, glottis & larynx.

Adverse Reactions

Nausea, vomiting, diarrhoea, dizziness, fatigue, headache, abdominal pain, cough. Rarely, symptomatic hypotension. Anaphylactic reactions, Stevens-Johnson, thrombocytopenia.

View ADR Monitoring Form

Drug Interactions

K-sparing agent, lithium, NSAIDs, ciclosporin, digoxin, capsaicin, antidiabetic agent or insulin.

MIMS Class

ACE Inhibitors/Direct Renin Inhibitors

ATC Classification

C09AA05 - ramipril ; Belongs to the class of ACE inhibitors. Used in the treatment of cardiovascular disease.

Thai FDA Category

Presentation/Packing

Form

Vaspril tab 10 mg

Packing/Price

10 × 10's

Form

Vaspril tab 2.5 mg

Packing/Price

10 × 10's

Form

Vaspril tab 5 mg

Packing/Price

10 × 10's

Vaspril

ramipril

Manufacturer:

Siam Bheasach

Distributor:

Siam Pharmaceutical