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Frequency of liver function tests: Before starting treatment and then after around 3 weeks, after around 6 weeks (end of acute phase), after around 12 and 24 weeks (end of maintenance phase) and thereafter when clinically indicated.
When increasing the dosage, liver function tests should again be performed at the same frequency as when initiating treatment.
Any patient who develops increased serum transaminases should have liver function tests repeated within 48 hours.
