Sign Out
TS-ONE is contraindicated in the following patients: Patients with a history of hypersensitivity to the ingredients of TS-ONE.
Patients with severe bone marrow depression [Bone marrow depression may be aggravated].
Patients with severe renal disorder [The urinary excretion of Gimeracil, a catabolic enzyme inhibitor of fluorouracil (5-FU), is markedly decreased, thereby the blood concentration of 5-FU is increased. These suggest that adverse reactions such as bone marrow depression may be enhanced (See Pharmacology: Pharmacokinetics under Actions)].
Patients with severe hepatic disorder [Hepatic disorder may be aggravated].
Patients receiving treatment with other fluoropyrimidine-group anti-cancer drugs including combination therapies with them (See Interactions).
Patients receiving treatment with flucytosine (See Interactions).
Pregnant women or women suspected of being pregnant (See Use in Pregnancy & Lactation).
