The dose must be adjusted carefully depending on the body surface area if methotrexate is used for the treatment of neoplastic diseases.
Important warning about the dosage of methotrexate tablet (methotrexate): In the treatment of psoriasis and Rheumatoid arthritis, methotrexate tablet (methotrexate) must only be used once a week. Dosage errors in the use of methotrexate tablet (methotrexate) can result in serious adverse reactions, including death. Read the summary of product characteristics very carefully.