Talafil Dosage/Direction for Use

Recommended Dose: Erectile dysfunction in adult men: The recommended dose is 10 mg taken prior to anticipated sexual activity and without regard to food. In those patients in whom tadalafil 10 mg does not produce an adequate effect, 20 mg might be tried. It may be taken at least 30 minutes prior to sexual activity.
The maximum dose frequency is once per day.
5 mg Tablet: Tadalafil 10 and 20 mg is intended for use prior to anticipated sexual activity and is not recommended for continuous daily use.
In responder patients to on-demand regimen who anticipate a frequent use of tadalafil (i.e., at least twice weekly) a once daily regimen with the lowest doses of tadalafil might be considered suitable, based on patient choice and the physician's judgement.
In these patients, the recommended dose is 5 mg taken once a day at approximately the same time of day. The dose may be decreased to 2.5 mg once a day based on individual tolerability.
The appropriateness of continued use of the daily regimen should be reassessed periodically.
10 mg & 20 mg Tablet: Continuous daily use of the medication is strongly discouraged because the long-term safety after prolonged daily dosing has not been established and also because the effect of tadalafil usually lasts for long than one day.
Benign prostatic hyperplasia in adult men (for 5 mg only): The recommended dose is 5 mg, taken at approximately the same time every day with or without food. For adult men being treated for both benign prostatic hyperplasia and erectile dysfunction the recommended dose is also 5 mg taken at approximately the same time every day.
Use in elderly men: Dose adjustments are not required in elderly patients.
Use in men with impaired renal function: Dose adjustments are not required in patients with mild to moderate renal impairment. For patients with severe renal impairment, 10 mg is the maximum recommended dose (for on-demand treatment for 5 mg).
5 mg Tablet: Once-a-day dosing of 2.5 or 5 mg tadalafil both for the treatment of erectile dysfunction or benign prostatic hyperplasia is not recommended in patients with severe renal impairment.
Use in men with impaired hepatic function: There is limited clinical data on the safety of tadalafil in patients with severe hepatic impairment (Child-Pugh class C); if prescribed, a careful individual benefit/risk evaluation should be undertaken by the prescribing physician. There are no available data about the administration of doses higher than 10 mg of tadalafil to patients with hepatic impairment.
5 mg Tablet: For the treatment of erectile dysfunction using on-demand tadalafil, the recommended dose of tadalafil is 10 mg taken prior to anticipated sexual activity and with or without food.
Once-a-day dosing both for the treatment of erectile dysfunction and benign prostatic hyperplasia has not been evaluated in patients with hepatic impairment; therefore, if prescribed, a careful individual benefit/risk evaluation should be undertaken by the prescribing physician.
10 mg & 20 mg Tablet: The recommended dose is 10 mg taken prior to anticipated sexual activity and without regard to food.
Use in men with diabetes: Dose adjustments are not required in diabetic patients.
Use in children and adolescents: Tadalafil should not be used in individual below 18 years of age.
Mode of administration: Tadalafil is administered orally and without regard to meals.