Sugril Dosage & Drug Information

Concise Prescribing Info

Contents

Glibenclamide

Indications/Uses

NIDDM.

Dosage/Direction for Use

Initially 2.5 mg daily, increasing by 2.5 mg every 3-5 days until diabetic control is obtained. Max daily dose: 15 mg. Max single dose: 10 mg.

Administration

Should be taken with food.

Contraindications

IDDM. Patients w/ ketoacidosis, severe infections, stress, trauma. Severe renal, hepatic or thyroid impairment. Acute porphyria.

Special Precautions

Elderly. Excessive exercise. Hypoglycemia.

Adverse Reactions

Cholestatic jaundice. Allergic dermatologic & hematologic reactions. GI disturbances, metallic taste. Headache, dizziness, paresthesia.

View ADR Monitoring Form

Drug Interactions

Potentiation of hypoglycemia by chloramphenicol, sulfonamides, coumarin, NSAIDs, salicylates, clofibrate & cimetidine. Hypoglycemic effect decreased by rifampicin, thiazide diuretics, corticosteroids, OC & β-blockers.

MIMS Class

Antidiabetic Agents

ATC Classification

A10BB01 - glibenclamide ; Belongs to the class of sulfonylureas. Used in the treatment of diabetes.

Thai FDA Category

Presentation/Packing

Form

Sugril tab 5 mg

Packing/Price

10 × 10's

Sugril

glibenclamide

Manufacturer:

Siam Bheasach

Distributor:

Siam Pharmaceutical