Silatio Dosage & Drug Information

Concise Prescribing Info

Contents

Sildenafil citrate

Indications/Uses

Pulmonary arterial HTN in adults to improve exercise ability & delay clinical worsening.

Dosage/Direction for Use

20 mg tid. Administer doses 4-6 hr apart.

Administration

May be taken with or without food.

Contraindications

Hypersensitivity. Concomitant use w/ organic nitrates or riociguat.

Special Precautions

Vasodilation may occur. Pulmonary veno-occlusive disease. Hearing or visual impairment. Pulmonary HTN secondary to sickle cell disease. Ped patients.

Adverse Reactions

Epistaxis, headache, dyspepsia, flushing, insomnia, erythema, dyspnea & rhinitis.

View ADR Monitoring Form

Drug Interactions

Additive BP-lowering effects w/ α-blockers & amlodipine. Concomitant use w/ ritonavir & other potent CYP3A inhibitors; phosphodiesterase-5 inhibitors.

MIMS Class

Other Antihypertensives

ATC Classification

C02KX - Antihypertensives for pulmonary arterial hypertension ; Used in the treatment of pulmonary arterial hypertension.
G04BE03 - sildenafil ; Belongs to the class of drugs used in erectile dysfunction.

Thai FDA Category

Presentation/Packing

Form

Silatio FC tab 20 mg

Packing/Price

10 × 10's

Silatio

sildenafil

Manufacturer:

Unison

Distributor:

Medline

Marketer:

Medline