Concomitant Medication: Advise patients to inform their physician if they are taking or plan to take any prescription or over-the-counter drugs since there is a potential for interactions.
Strong and Moderate CYP 3A inhibitors and Pg-p inhibitors: Advise patients to inform their physician if they use strong (e.g., ketoconazole, itraconazole, clarithromycin, telithromycin, nelfinavir, saquinavir, indinavir, ritonavir) or moderate CYP 3A inhibitors (e.g., aprepitant, erythromycin, diltiazem, verapamil, fluconazol) or P-gp inhibitors (e.g., cyclosporine) (see Dosage and Administration, Contraindications, Warnings and Precautions and Drug Interactions).
Nursing: Advise patients not to breastfeed an infant if they are taking Samsca (see Use In Pregnancy & Lactation).