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Epilepsy: Topiramate is used as initial monotherapy or adjunctive therapy in patients older than 2 years for the management of partial-onset, primary generalized tonic-clonic seizure.
Topiramate is used as adjunctive therapy in patients older than 2 years for the management of seizures associated with Lennox-Gastaut syndrome.
Migraine Prophylaxis: Topiramate is also used in the prophylaxis of migraine headache in adults and adolescent ≥12 years.
Note: The efficacy of the drug in the acute treatment of migraine headache has not been established.
