The overdosage following oral ingestion of the commercially available ophthalmic solution is unlikely given the limited amount (1 mg/mL) of olopatadine. Single oral olopatadine doses up to 360 mg have been well tolerated in humans. However, symptoms of antihistamine overdosage may include drowsiness in adults and, initially, agitation and restlessness, followed by drowsiness, in children. If overdosage occurs, symptomatic or supportive treatment is recommended, taking into account any concomitantly ingested medications.
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