Femara Dosage & Drug Information

Concise Prescribing Info

Contents

Letrozole

Indications/Uses

Adjuvant treatment of postmenopausal women w/ hormone receptor +ve early breast cancer. Extended adjuvant treatment of early breast cancer in postmenopausal women who have received prior standard adjuvant tamoxifen therapy. 1st-line treatment in postmenopausal women w/ hormone-dependent advanced breast cancer. Advanced breast cancer in women w/ natural or artificially induced postmenopausal status, who have previously been treated w/ anti-estrogens.

Dosage/Direction for Use

Adult & elderly: 2.5 mg once daily.

Administration

May be taken with or without food.

Contraindications

Premenopausal endocrine status. Pregnancy & lactation.

Special Precautions

Patients w/ CrCl <10 mL/min; severe hepatic impairment (Child-Pugh score C). Monitor bone health. May impair ability to drive or operate machinery.

Adverse Reactions

Hot flushes, nausea, fatigue, arthralgia. Anorexia, increased appetite, hypercholesterolemia, depression, headache, dizziness, vomiting, dyspepsia, constipation, diarrhoea, alopecia, increased sweating, rash, myalgia, bone pain, osteoporosis, bone fractures, peripheral oedema, wt increase.

View ADR Monitoring Form

MIMS Class

Cancer Hormone Therapy

ATC Classification

L02BG04 - letrozole ; Belongs to the class of enzyme inhibitors. Used in treatment of neoplastic diseases.

Thai FDA Category

Presentation/Packing

Form

Femara film-coated tab 2.5 mg

Packing/Price

30's

Femara

letrozole

Manufacturer:

Novartis

Distributor:

Zuellig Pharma