Erectile dysfunction 10 mg prior to anticipated sexual activity as needed.
Patient whom tadalafil 10 mg does not produce adequate effect Max daily dose: 20 mg. May be taken from 30 min to 36 hr pior to sexual activity.
Patient who anticipate a frequent use of Zenavil (ie, at least 2x wkly) 2.5 mg once daily at approx same time every day w/o regard to timing of sexual activity.
BPH 5 mg at approx same time every day. Therapy initiated w/ finasteride: 5 mg at approx same time every day up to 26 wk.
Erectile dysfunction & BPH 5 mg at approx same time every day w/o regard to timing of sexual activity.
Moderate renal impairment (CrCl 31-50 mL/min) Initially 5 mg once daily. Max dose: 10 mg not more than once in every 48 hr.
Severe renal impairment (CrCl <30 mL/min or on hemodialysis) Max dose: 5 mg not more than once in every 72 hr.
Hepatic impairment 10 mg prior to anticipated sexual activity.
Patient taking CYP3A4 inhibitors (eg, ketoconazole or ritonavir) Max dose: 10 mg not to exceed once every 72 hr when used as needed. Max once daily dose: 2.5 mg.
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