Severe acute bleeding from upper GIT, oesophageal varices Start by a slow IV inj of 250 mcg as loading dose, then immediately followed by an IV infusion at a rate of 250 mcg/hr. Continue treatment for 48-72 hr once haemorrhage has stopped (<12-24 hr) to avoid rebleeding.
Adjuvant treatment in pancreatic, biliary & intestinal fistulae Continuous infusion of 250 mcg/hr until closure of the fistula (2-20 days). Continue treatment for 1-3 days (stopping progressively) once fistula has been closed.
Prophylactic treatment of post-op complications following pancreatic surgery 250 mcg/hr at the beginning of surgical intervention for 5 days.
Adjuvant treatment in diabetic ketoacidosis 100-500 mcg/hr infusion associated w/ insulin therapy (bolus of 10 IU + infusion of 1-4.8 IU/hr).
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