Bronchitis; neutropenia; IRRs (HTN, nausea, rash, pyrexia, pruritus, urticaria, throat irritation, hypotension, rhinitis, fatigue, peripheral edema); alopecia; headache; decreased IgG levels. Sinusitis; paraesthesia, dizziness; anxiety; dyspepsia, diarrhoea; arthralgia. TEN. NHL & CLL: Bacterial & viral infections; leucopenia, febrile neutropenia, thrombocytopenia; angioedema; chills, asthenia. Sepsis, pneumonia, febrile infection, herpes zoster, resp tract & fungal infections, infections of unknown aetiology, acute bronchitis, hepatitis B; anaemia, pancytopenia, granulocytopenia; hypersensitivity; hyperglycaemia, decreased wt, face edema, increased LDH, hypocalcaemia; hypoaesthesia, agitation, insomnia, vasodilatation; lacrimation disorder, conjunctivitis; tinnitus, ear pain; MI, arrhythmia, atrial fibrillation, tachycardia, cardiac disorder; orthostatic hypotension; bronchospasm, resp disease, chest pain, dyspnoea, increased cough; vomiting, abdominal pain, dysphagia, stomatitis, constipation, anorexia; sweating, night sweats, skin disorder; hypertonia, myalgia, back & neck pain, pain; tumour pain, flushing, malaise, cold syndrome, shivering, multi-organ failure. Interstitial lung disease; GI perforation. RA: Upper resp tract & urinary tract infection; hot flush, rigors, oropharyngeal pain, erythema; decreased IgM levels. Gastroenteritis, tinea pedis; hypercholesterolemia; migraine, sciatica; depression; gastro-oesophageal reflux, mouth ulceration, upper abdominal pain; musculoskeletal pain, osteoarthritis, bursitis.