Quinidine - oral


Patient Medicine Information
Why do I need this medicine?
Quinidine is used to treat abnormal heart rhythm.

This medicine may be used to treat other conditions as decided by your doctor.
How do I take this medicine?
Take Quinidine exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

You may take this medicine with food or milk to reduce any stomach discomfort that it may cause. Try to take it at the same time each day.

This medicine is available as a conventional or extended-release tablet.

If you are taking the extended-release type of tablet (usually labelled as "ER"), swallow it whole. Do not chew or crush the tablet. Extended-release tablets may be broken and split in half only if necessary.

Quinidine must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed by the doctor.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Do not take Quinidine if you ever had an allergic reaction (e.g. rashes, breathlessness, swollen eyes) to this medicine or any of its ingredients.

Alert your doctor if you have the following conditions:
  • history of immune thrombocytopenia (blood disorder caused by decrease number of platelets leading to excessive bleeding, easy bruising and multiple tiny red or purplish spots on the skin or the insides of the mouth)
  • heart block greater than 1st degree
  • delay in conduction (signals that controls the heartbeat)
  • myasthenia gravis (muscle weakness disorder)
As Quinidine may not be suitable for you.
What should I take note of while taking this medicine?
Inform your doctor if you have the following conditions:
  • other heart problems e.g. abnormally fast and erratic heartbeats
  • hypokalaemia (low potassium level in the blood)
  • hypomagnesaemia (low magnesium level in the blood)
  • G6PD deficiency (an inherited blood disorder where the body lacks a certain enzyme necessary for the proper functioning of red blood cells)
  • kidney disease
  • liver disease
Let your doctor know if you are pregnant or breastfeeding.

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly. Routine tests (e.g. complete blood count, heart, liver and kidney function) may be done while you are being treated with this medicine. Your doctor will advise you about how often you need to have these tests.
What side effects could I experience?
Quinidine may cause any of the following side effects: diarrhoea, nausea, vomiting, dizziness, headache, and tiredness.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • rashes, breathlessness, swelling of the face, eyes or mouth
  • fast or irregular heartbeat
  • yellowing of the skin or eyes, abdominal pain, dark coloured urine, tiredness, swelling in the legs and ankles
  • severe rashes, especially with multiple tiny red or purple spots on the skin and sometimes on the inside of the mouth
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking any of these medicines:
  • medicines for heart disease or high blood pressure e.g. verapamil, diltiazem, digoxin
  • medicines for glaucoma (increased pressure in the eye)
  • water pills or medicines for water retention
  • medicines for epilepsy (fits or seizures) e.g. phenytoin, phenobarbital
  • medicines used for blocking pain and sensation, and relaxing the muscles during procedures e.g. succinylcholine, tubocuraraine, pancuronium
  • rifampicin (medicine to treat TB, a lung infection known as tuberculosis)
  • cimetidine (medicine that reduces stomach acid production)
  • ketoconazole (medicine to treat fungal infection)
  • warfarin (blood-thinning medicine)
This list does not include all medicines that may interact with Quinidine.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements, and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.

Avoid excessive consumption of grapefruit or grapefruit juice (more than 1 litre a day).
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Protect from light.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on quinidine - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2024 MIMS. All rights reserved. Powered by MIMS.com
Exclusive offer for doctors
Register for a MIMS account and receive free medical publications worth $139 a year.
Already a member? Sign in
Exclusive offer for doctors
Register for a MIMS account and receive free medical publications worth $139 a year.
Already a member? Sign in