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Used in conjunction with other antituberculosis drugs in the treatment of pulmonary and extrapulmonary tuberculosis and alone in the prophylaxis of tuberculosis.
To reduce the development of drug-resistant bacteria and maintain the effectiveness of pdp-ISONIAZID and other antibacterial drugs, pdp-ISONIAZID should be used only to treat infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.
