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Exocrine pancreatic insufficiency
Adult: In cases due to cystic fibrosis and other conditions (e.g. chronic pancreatitis or pancreatectomy): Usual dose with each meal: 5,000-56,000 units of lipase activity (with varying proportions of protease and amylase activity, depending on the preparation). Dose is adjusted according to individual needs, amount and type of food consumed, and dosage form. Dosage recommendation may vary among individual products and between countries (refer to specific product and country guidelines).
Child: In cases caused by cystic fibrosis: Infants Initially, 2,000-5,000 units lipase/feeding; <4 years Initially, 1,000 units lipase/kg/meal; ≥4 years Initially, 500 units lipase/kg/meal. All doses must be at a Max daily dose of 10,000 units lipase/kg/day. Dose is adjusted according to individual needs, amount and type of food consumed, and dosage form. Dosage recommendation may vary among individual products and between countries (refer to specific product and country guidelines).
Child: In cases caused by cystic fibrosis: Infants Initially, 2,000-5,000 units lipase/feeding; <4 years Initially, 1,000 units lipase/kg/meal; ≥4 years Initially, 500 units lipase/kg/meal. All doses must be at a Max daily dose of 10,000 units lipase/kg/day. Dose is adjusted according to individual needs, amount and type of food consumed, and dosage form. Dosage recommendation may vary among individual products and between countries (refer to specific product and country guidelines).
