Pregnancy: The safety of moxifloxacin in human pregnancy has not been evaluated. Animal studies have shown reproductive toxicity (see Pharmacology: Toxicology under Actions). The potential risk for humans is unknown. Due to the experimental risk of damage by fluoroquinolones to the weight-bearing cartilage of immature animals and reversible joint injuries described in children receiving some fluoroquinolones, moxifloxacin must not be used in pregnant women (see Contraindications).
Breastfeeding: There is no data available in lactating or nursing women. Preclinical data indicate that small amounts of moxifloxacin are secreted in milk. In the absence of human data and due to the experimental risk of damage by fluoroquinolones to the weight-bearing cartilage of immature animals, breast-feeding is contraindicated during moxifloxacin therapy (see Contraindications).
Fertility: Animal studies do not indicate impairment of fertility (see Pharmacology: Toxicology under Actions).