Frequently monitor K levels. Patients w/ NYHA class IV heart failure; medical history of atrial fibrillation. Observe for potential CNS effects in patients w/ impaired blood-brain barrier (BBB) & clinically important disruptions to the BBB (eg, primary brain malignancies, CNS metastases or other inflammatory conditions, active multiple sclerosis, advanced Alzheimer's disease). Contains Na <1 mmol/vial. Concomitant use of sedating antihistamines, opioid analgesics or other CNS depressants. May affect ability to drive or operate hazardous machinery; possible somnolence &/or dizziness. Not recommended for severe hepatic impairment. Avoid use during pregnancy. Lactation. Childn 0-17 yr. Elderly ≥65 yr.
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