Hialid

Sodium hyaluronate.

Each mL of ophthalmic solution contains sodium hyaluronate 1 or 3 mg, respectively.
It has a pH of 6-7 and an osmotic pressure ratio of 0.9-1.1.
Excipients/Inactive Ingredients: Hialid also contains ε-aminocaproic acid, disodium edetate hydrate, propylene glycol and benzalkonium chloride as additives.

Pharmacology: Mechanism of Action: Sodium hyaluronate is bound to fibronectin and accelerates the adhesion and extension of epithelial cells. It also has an excellent water-holding property because each sodium hyaluronate molecule can retain many water (H₂O) molecules.
Acceleration of Corneal Wound Healing: Topical application of sodium hyaluronate ophthalmic solution accelerates the wound healing of corneal epithelium in rabbits.
Acceleration of Corneal Epithelial Extension: Sodium hyaluronate accelerates the extension of corneal epithelial cells in isolated strips of cultured rabbit cornea.
Prevention of Corneal Drying: When applied to isolated strips of rabbit cornea, sodium hyaluronate is significantly more effective than artificial tears in preventing corneal drying.
Water Retentive Property: 0.3%: Weight loss of agar plugs due to water evaporation was prevented concentration-dependently by placing drops of 0.1%-1.0% sodium hyaluronate solutions atop the plugs.

Relief of symptoms associated with dry eyes.
0.3%: Keratoconjunctival epithelial disorder resulting from the following diseases:
Intrinsic diseases such as Sjögren's syndrome, Stevens-Johnson syndrome and sicca syndrome (dry eye).
Extrinsic diseases caused by surgery, drugs, trauma, contact lens wearing, etc.

For ophthalmic use only.
Usually, instill 1 drop a time 5-6 times daily. The dosage may be adjusted according to the patient's symptoms.

If the following adverse reactions or symptoms occur, discontinue Hialid and consult a physician.
Adverse Reactions: Blepharitis, eyelid dermatitis, itching, irritation, conjunctivitis, conjunctival infection, corneal lesion eg, keratitis superficialis diffusa, eye discharge, foreign body sensation in eye, eye discharge, eye pain.

The tip of the eyedropper must not come into contact with the eyes at the time of application.
Hialid must not be used while wearing soft contact lenses.

Store at room temperature (1-30°C).

Ophthalmic Lubricants

S01XA20 - artificial tears and other indifferent preparations ; Belongs to the class of other ophthalmologicals.

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