Hypersensitivity to gliclazide or to any of the excipients listed in Description, other sulphonylureas or sulphonamides; Insulin-dependent diabetes (Type I); Diabetic pre-coma and coma, diabetic ketoacidosis; Severe renal or hepatic insufficiency (in these cases the use of insulin is recommended); Treatment with miconazole (see Interactions); Pregnancy and lactation (see Use in Pregnancy & Lactation).