PI IV 300-600 mg/kg every 3-4 wk. Initial infusion rate: 1 mg/kg/min, then may be gradually increased to a max of 8 mg/kg/min.
Patient routinely receives <400 mg/kg dose every 3-4 wk & at risk of measles exposure Administer at least 400 mg/kg prior to expected measles exposure.
Patient exposed to measles Administer 400 mg/kg immediately after exposure.
SC Individualized dosage based on clinical response & serum IgG trough levels, 1 wk after last IV infusion.
ITP IV 2 g/kg divided in 2 doses of 1 g/kg given on 2 consecutive days or into 5 doses of 0.4 g/kg on 5 consecutive days. Initial infusion rate: 1 mg/kg/min, then may be gradually increased to a max of 8 mg/kg/min.
CIDP IV Total loading dose:
2 g/kg in divided doses over 2-4 consecutive days. Maintenance dose: 1 g/kg over 1 day or in 2 divided doses of 0.5 g/kg given on 2 consecutive days every 3 wk. Initial infusion rate: 2 mg/kg/min, then may be gradually increased to a max of 8 mg/kg/min.