Prophylaxis of migraine
Adult: In patients who have at least 4 migraine days monthly: 100 mg every 3 months via infusion over approx 30 minutes, may increase dose to 300 mg every 3 months if necessary. Evaluate the need for dose escalation within the 1st 3 months; increased dose is given on the next scheduled date. Assess treatment 6 months after initiation.