Symptomatic relief of mild to moderate vasomotor symptoms associated w/ menopause; prevention of postmenopausal osteoporosis Continuous sequential therapy: Oestrogen is dosed continuously, 10 mg dydrogesterone is added for the last 14 days of every 28 day cycle. Cyclic therapy: Oestrogen is dosed cyclically w/ a treatment-free interval (usually 21 days on & 7 days off), 10 mg dydrogesterone is added for the last 12-14 days of oestrogen therapy.
Inadequate progestational response revealed by ultrasound or endometrial biopsies 20 mg dydrogesterone.
Dysmenorrhoea 10 mg bd from day 5-25 of menstrual cycle.
Endometriosis 10 mg bd-tds from day 5-25 of cycle or continuously.
Dysfunctional bleeding To arrest bleeding: 10 mg bd w/ oestrogen for 5-7 days. To prevent bleeding: 10 mg bd w/ oestrogen from day 11-25 of cycle.
Amenorrhoea Oestrogen once daily from day 1-25 of cycle together w/ 10 mg dydrogesterone bd from day 11-25 of cycle.
Irregular cycles 10 mg bd from day 11-25 of cycle.
Threatened miscarriage 40 mg at once then 10 mg every 8 hr until symptoms remit.
Habitual miscarriage 10 mg bd until 20th wk of pregnancy.
Infertility due to luteal insufficiency 10 mg daily from day 14-25 of cycle. Continue therapy for at least 6 consecutive cycles.
Luteal support as part of ART treatment 10 mg tds starting at the day of oocyte retrieval & continuing for 10 wk if pregnancy is confirmed.
Sign Out
