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Injection: For general medical reasons, Dosanac should only be prescribed during pregnancy if its use is mandatory. Following oral doses of 100 mg daily, on active substance could be found in the breast milk. (Limit of detection: 10 ng/ml).
Use of NSAIDs at about 20 weeks gestation or later in pregnancy may cause foetal renal dysfunction leading to oligohydramnios and in some cases, neonatal renal impairment. These adverse outcomes are seen, on average, after days to weeks of treatment, although oligohydramnios has been infrequently reported as soon as 48 hours after NSAID initiation. Oligohydramnios is often, but not always, reversible with treatment discontinuation.
