Monotherapy for colon, colorectal or breast cancer Initially 1,250 mg/m
2 bd for 2 wk, followed by a 7-day rest period. Adjuvant treatment w/ stage III colon cancer is recommended for a total of 6 mth.
Combination therapy for breast cancer w/ docetaxel Initially 1,250 mg/m
2 bd for 2 wk, followed by a 7-day rest period plus docetaxel 75 mg/m
2 given as 1-hr IV infusion every 3 wk.
Combination therapy for colon & colorectal cancer Initially 1,000 mg/m
2 bd for 2 wk, followed by a 7-day rest period. Adjuvant treatment w/ stage III colon cancer is recommended for a total of 6 mth.