Apo-Fluticasone

Apo-Fluticasone

fluticasone

Manufacturer:

Apotex

Distributor:

Pharmaforte
Concise Prescribing Info
Contents
Fluticasone propionate
Indications/Uses
Prophylaxis & treatment of seasonal allergic rhinitis including hay fever & perennial rhinitis.
Dosage/Direction for Use
Adult, childn >12 yr & elderly 2 sprays into each nostril once daily preferably in the morning. May require 2 sprays into each nostril bd in some cases. Max daily dose: 4 sprays into each nostril. Childn 4-11 yr 1 spray into each nostril once daily preferably in the morning. May require 1 spray into each nostril bd in some cases. Max daily dose: 2 sprays into each nostril.
Special Precautions
Treat infections of the nasal airways appropriately. Patients w/drawing from systemic steroid treatment & commencing therapy w/ intranasal fluticasone propionate. Additional therapy may be needed during abnormally heavy challenge of summer allergens. Systemic effects at high doses for prolonged periods may occur. Regularly monitor height of childn receiving prolonged treatment. Clinically significant adrenal suppression may result w/ higher than recommended doses. Consider referral to an ophthalmologist if patient presents w/ symptoms eg, blurred vision or other visual disturbances; risk of central serous chorioretinopathy. Avoid concomitant use w/ ritonavir. Pregnancy & lactation.
Adverse Reactions
Epistaxis. Headache, unpleasant taste & smell; dryness & irritation of the nose & throat.
Drug Interactions
May greatly increase plasma conc by ritonavir, resulting in markedly reduced serum cortisol conc. Potentially increased systemic exposure of CYP450 3A4 inhibitors (eg, ketoconazole).
MIMS Class
Nasal Decongestants & Other Nasal Preparations
ATC Classification
R01AD08 - fluticasone ; Belongs to the class of topical corticosteroids used for prophylaxis and treatment of allergic rhinitis.
Presentation/Packing
Form
Apo-Fluticasone nasal spray 50 mcg/spray
Packing/Price
120 dose x 1's
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