Alzer Description

Each film coated tablet contains 5 mg Donepezil hydrochloride equivalent to 4.56 mg donepezil free base, or 10 mg Donepezil hydrochloride.
Donepezil hydrochloride is a reversible inhibitor of the enzyme acetylcholinesterase, known chemically as (±)-2, 3-dihydro-5, 6-dimethoxy2-[[1-(phenylmethyl)-4- piperidinyl]methyl]-1H-inden-1-one hydrochloride. Donepezil hydrochloride is commonly referred to in the pharmacological literature as E2020. It has an empirical formula of C24H29NO3HCl and a molecular weight of 415.96. Donepezil hydrochloride is a white crystalline powder and is freely soluble in chloroform, soluble in water and in glacial acetic acid, slightly soluble in ethanol and in acetonitrile and practically insoluble in ethyl acetate and in n-hexane.
Donepezil hydrochloride is available for oral administration in film-coated tablets containing 5 mg of donepezil hydrochloride.
Inactive ingredients in 5 mg tablets are lactose monohydrate (Pharmatose 200M), corn starch (Extra white maize starch), microcrystalline cellulose (Avicel PH 101), hydroxypropyl cellulose (Klucel-LF), Purified water, microcrystalline cellulose (Avicel PH 102), magnesium stearate, Opadry white 03F58763 (Hypromellose, Titanium dioxide, Polyethylene glycol/Macrogol, Talc).