Akilen Adverse Reactions

Ofloxacin, as fluoroquinolones in general has been well tolerated and adverse reactions seldom were severe enough to require discontinuation of therapy.
Adverse reactions affect the gastro-intestinal tract and the central nervous system most frequently e.g. nausea, headache, dizziness and insomnia.
Other adverse effects of the gastro-intestinal tract include vomiting, diarrhea, decreased appetite, abdominal pain and dry mouth.
Hypersensitivity reactions: skin rash and pruritus.
Laboratory abnormalities also occur infrequently and are minor and reversible. These include elevations in BUN, serum creatinine levels, SGOT, SGPT, alkaline phosphate, gamma-GT, total bilirubin, decrease in leucocytes, erythrocytes, Hb and platelet counts, and increase in eosinophil.
Possibility of Tendon Disorders, eg. Tendon Rupture.
Nervous system disorders (frequency not known): Peripheral neuropathy (that may be irreversible) and polyneuropathy.
Cardiac disorders: Not known: ventricular arrythmia and torsades de pointes (reported predominantly in patients with risk factors for QT prolongation), ECG QT prolonged.
Exacerbation of Myasthenia Gravis.