Evaluate possibility of allergic reactions in persons sensitive to the components of the vaccine. Not to be administered intravascularly, intradermally, SC or into the buttocks. Not to be used for treatment of disease caused by
Bordetella pertussis, Corynebacterium diphtheriae or
Clostridium tetani infections. Not to be given as fractional doses (<0.5 mL). Syncope may occur; place procedures to prevent falling injury & manage syncopal reactions. May not protect 100% of vaccinated persons. Postpone vaccination in case of acute or febrile disease. Possible inj site hematoma in persons w/ any bleeding disorders (eg, hemophilia or thrombocytopenia) or in persons on anticoagulant therapy. Immunocompromised persons. Vaccination of persons w/ chronic immunodeficiency (eg, HIV) is recommended even if immune response might be limited. Not to be administered to individuals w/ progressive or unstable neurological disorders, uncontrolled epilepsy or progressive encephalopathy until treatment regimen has been established & condition has stabilized. Carefully consider use if Guillain-Barré syndrome occurred w/in 6 wk of receipt of prior tetanus toxoid containing vaccine. Possible CNS demyelinating diseases, peripheral & cranial mononeuropathies. Pregnancy; may be administered during 2nd or 3rd trimester. Lactation. Not indicated for immunization of childn <4 yr.
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