IV infusion Adult & adolescent 12 to <18 yr weighing ≥33 kg 600 mg every 12 hr over 5-60 min.
Treatment of cSSTI confirmed or suspected to be caused by Staph aureus w/ MIC <2 mg/L 600 mg every 12 hr over 5-60 min.
Treatment of adult w/ cSSTI confirmed or suspected to be caused by Staph aureus w/ 2-4 mg/L MIC 600 mg every 8 hr over 120 min.
Adolescent 12 yr to <18 yr w/ cSSTI 600 mg every 12 hr over 5-60 min for 5-14 days;
cSSTI in adult when caused by Staph aureus w/ 2-4 mg/L MIC 600 mg every 8 hr over 120 min for 5-14 days;
CAP 600 mg every 12 hr over 5-60 min for 5-7 days.
Childn ≥12 yr to <18 yr 12 mg/kg every 8 hr over 5-60 min;
≥2 yr to <12 yr 12 mg/kg every 8 hr over 5-60 min;
≥2 mth to <2 yr 8 mg/kg every 8 hr over 5-60 min.
Renal impairment in adult & adolescent 12 yr to <18 yr w/ CrCl >30 to ≤50 mL/min 400 mg every 12 hr over 5-60 min (cSSTI & CAP), 400 mg every 8 hr over 120 min (cSSTI caused by
Staph aureus w/ MIC 2-4 mg/L);
≥15 to ≤30 mL/min 300 mg every 12 hr over 5-60 min (cSSTI & CAP), 300 mg every 8 hr over 120 min (cSSTI caused by
Staph aureus w/ MIC 2-4 mg/L);
ESRD including hemodialysis 200 mg every 12 hr over 5-60 min (cSSTI & CAP), 200 mg every 8 hr over 120 min (cSSTI caused by
Staph aureus w/ MIC 2-4 mg/L).
Renal impairment in childn ≥12 yr to <18 yr & ≥2 yr to <12 yr w/ CrCl >30 to ≤50 mL/min 8 mg/kg every 8 hr over 5-60 min;
≥12 yr to <18 yr & ≥2 yr to <12 yr w/ CrCl ≥15 to ≤30 mL/min 6 mg/kg every 8 hr over 5-60 min.
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