SchizophreniaAdult Initially 5-10 mg once daily w/ a target dose of 10 mg/day w/in several days. Further adjust dose in increments/decrements of 5 mg once daily if necessary. Maintenance dose: 10-20 mg/day. Adolescent Initially 2.5 mg or 5 mg w/ a target dose of 10 mg/day. Adjust dose in increments/decrements of 2.5 mg or 5 mg if necessary. Bipolar I disorder (manic or mixed episodes)Adult Monotherapy: 10-15 mg once daily. Adjust dose in increments/decrements of 5 mg once daily if necessary. Adjunctive treatment: 10 mg once daily w/ lithium or valproate. Adolescent Initially 2.5 mg or 5 mg w/ a target dose of 10 mg/day.
Increased risk of death in elderly patients w/ dementia. Not for the treatment of patients w/ dementia-related psychosis & Alzheimer's disease. Possibility of suicide attempt. Neuroleptic malignant syndrome. Hyperlipidemia. Wt gain. Risk of developing tardive dyskinesia. Patients w/ known CV disease (history of MI or ischemia, heart failure or conduction abnormalities), cerebrovascular disease & conditions which predispose patients to hypotension. History of seizures or conditions that potentially lower seizure threshold eg, Alzheimer's dementia. Elevation in core body temp. Hyperprolactinemia. Not intended for use in ped patients who exhibits symptoms secondary to environmental factors &/or other primary psychiatric disorders. Concomitant administration of IM olanzapine w/ parenteral benzodiazepine. Monitor regularly for worsening of glucose control; symptoms of hyperglycemia including polydipsia, polyuria, polyphagia, & weakness. Perform fasting blood glucose testing & lipid profile at the beginning of, & periodically during treatment. Potential for cognitive & motor impairment. Pregnancy. Do not breast-feed. Childn <13 yr.
Drowsiness, dizziness, restlessness, unusual behavior, depression, difficulty falling asleep or staying asleep, weakness, difficulty walking, constipation, wt gain, dry mouth, arms, legs, back, or joints pain, breast enlargement or discharge, late or missed menstrual periods, decreased sexual ability.
Sign Out
