Xenical

Xenical

orlistat

Manufacturer:

Zuellig Pharma

Distributor:

Zuellig
Concise Prescribing Info
Contents
Orlistat
Indications/Uses
In conjunction w/ a mildly hypocaloric diet, treatment of obese or overwt patients w/ associated comorbidities.
Dosage/Direction for Use
Administration
Should be taken with food: Take immediately before or during or up to 1 hr after each main meal. If a meal is missed or contains no fat, the dose may be omitted.
Contraindications
Hypersensitivity. Chronic malabsorption syndrome, cholestasis.
Special Precautions
Monitor cyclosporine plasma levels when co-administered w/ Xenical. Patients treated w/ concomitant oral anticoagulants. Intake of amiodarone. Pregnancy & lactation. Childn <12 yr.
Adverse Reactions
Oily spotting, flatus w/ discharge, fecal urgency, fatty/oily stool, oily evacuation, increased defecation, fecal incontinence (incidence of these increases the higher the fat content of the diet). Abdominal pain/discomfort, flatulence, liqd stools, soft stools, rectal pain/discomfort, tooth disorder, gingival disorder. Rarely, elevated transaminase or alkaline phosphatase level or hepatitis.
Drug Interactions
Inhibits absorption of oral fat soluble nutrient; decreased absorption of vit D, E & β-carotene. Reduction in cyclosporin plasma levels. Reduced therapeutic effect of amiodarone. Risk of convulsions w/ antiepileptic drugs. Warfarin or other oral anticoagulants. Increased GI events w/ high-fat diet.
MIMS Class
Anti-Obesity Agents
ATC Classification
A08AB01 - orlistat ; Belongs to the class of peripherally acting antiobesity products.
Presentation/Packing
Form
Xenical cap 120 mg
Packing/Price
21's (P865/pack)
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