Adult Gastric & duodenal ulcer 20 mg once daily, up to 8 wk for gastric ulcer & up to 6 wk for duodenal ulcer.
Reflux esophagitis 20 mg once daily for up to 4 wk or if necessary, up to 8 wk.
Recurrent & relapsing reflux esophagitis 10 mg once daily, may be increased to 20 mg once daily if necessary.
Prevention of recurrence of gastric or duodenal ulcer during low-dose aspirin or NSAIDs administration 10 mg once daily.
Adjunct to H. pylori eradication 20 mg vonoprazan + 750 mg amoxicillin hydrate + 200 mg clarithromycin bid for 7 days. May properly increase clarithromycin dose up to max 400 mg bid as the occasion demands. Alternatively, 20 mg vonoprazan + 750 mg amoxicillin hydrate + 250 mg metronidazole bid for 7 days may be used if the other treatment fails.
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