Search

Vaxol

Vaxol

cilostazol

Manufacturer:

Cathay YSS

Distributor:

Cathay YSS
Concise Prescribing Info
Contents
Cilostazol
Indications/Uses
Symptomatic treatment of intermittent claudication in patients w/o rest pain & no peripheral tissue necrosis.
Click to view Vaxol detailed prescribing information
Dosage/Direction for Use
Intermittent claudication 100 mg bid for up to 12 wk.
Click to view Vaxol detailed prescribing information
Overdosage
View Vaxol overdosage for action to be taken in the event of an overdose.
Administration
Should be taken on an empty stomach: Take at least 30 min before or 2 hr after meals.
Contraindications
Hypersensitivity. CHF of any severity. Hemostatic disorders or active pathologic bleeding eg, peptic ulcer or intracranial bleeding; history of ventricular arrhythmias, QT interval prolongation, severe renal impairment or moderate to severe hepatic impairment.
Click to view Vaxol detailed prescribing information
Warnings
For additional cautionary notes to warn of the potential risk of using the medicine... Click to view Vaxol detailed prescribing information
Special Precautions
CV risks & lesions including endocardial hemorrhage, hemosiderin deposition & fibrosis in left ventricle, hemorrhage & necrosis of smooth muscle in coronary artery wall, intimal thickening of coronary artery & coronary arteritis & periarteritis. Severe renal (CrCl <25 mL/min) & moderate to severe hepatic impairment. Pregnancy & lactation. Childn.
Click to view Vaxol detailed prescribing information
Adverse Reactions
Headache; palpitations, tachycardia; dizziness, abnormal stool, diarrhea, dyspepsia, flatulence, nausea; infection & peripheral edema, asthenia, gastritis, MI, CHF, postural hypotension, insomnia, anxiety, abnormal dreams, dyspnoea, pneumonia, cough, hypersensitivity reactions, DM, anaemia, haemorrhage, thrombocythaemia, myalgia & renal impairment.
Click to view Vaxol detailed prescribing information
Drug Interactions
Enhances effects of anticoagulant & antiplatelet agents. Decreased metabolism w/ antifungal drugs eg, imidazole. Increased levels & effects w/ CYP2C19 inhibitors (eg, delavirdine, fluvoxamine, gemfibrozil, INH, omeprazole & ticlopidine) & CYP3A4 inhibitors (eg, azole antifungal, clarithromycin, diclofenac, doxycycline, erythromycin, imatinib, INH, nefazodone, nicardipine, propofol, PIs, quinidine, telithromycin, verapamil & grapefruit juice). Decreased levels or effects w/ CYP3A4 inducers (eg, aminoglutethimide, carbamazepine, nafcillin, nevirapine, phenobarb, phenytoin & rifamycin). Enhanced antithrombotic effects w/ dasatinib. Decreased metabolism w/ macrolide antibiotics eg, clarithromycin, erythromycin & telithromycin. Increased risk of bleeding w/ NSAIDs & salicylates. Enhanced adverse or toxic effects w/ omeprazole & trepostinil. Enhanced effects w/ omega-3-acid ethyl esters.
Click to view Vaxol detailed prescribing information
Storage
View Vaxol storage conditions for details to ensure optimal shelf-life.
Description
View Vaxol description for details of the chemical structure and excipients (inactive components).
Action
View Vaxol mechanism of action for pharmacodynamics and pharmacokinetics details.
MIMS Class
Anticoagulants, Antiplatelets & Fibrinolytics (Thrombolytics)
ATC Classification
B01AC23 - cilostazol ; Belongs to the class of platelet aggregation inhibitors excluding heparin. Used in the treatment of thrombosis.
Presentation/Packing
Form
Vaxol FC tab 100 mg
Packing/Price
100's (P30.35/film-coated tab)
Form
Vaxol tab 50 mg
Packing/Price
100's (P1,092/box)
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Already a member? Sign in
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Already a member? Sign in