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Vasalat

Vasalat

amlodipine

Manufacturer:

Apotex

Distributor:

Patriot
Concise Prescribing Info
Contents
Amlodipine besilate
Indications/Uses
Management of HTN & prophylaxis of angina.
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Dosage/Direction for Use
Adult Usual dose: 5-10 mg once daily. Elderly & patient w/ hepatic function impairment Initially 2.5 mg. Angina Initially 5 mg. Childn 6-17 yr 2.5-5 mg once daily.
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Overdosage
View Vasalat overdosage for action to be taken in the event of an overdose.
Administration
May be taken with or without food.
Contraindications
Severe hypotension.
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Warnings
For additional cautionary notes to warn of the potential risk of using the medicine... Click to view Vasalat detailed prescribing information
Special Precautions
Hypersensitivity. Aortic stenosis; CHF. Monitor BP, ECG readings, heart rate; reduced frequency or severity of anginal attacks; decreased nitrate consumption. Gingival hyperplasia. W/drawal prior to surgery. Increased angina &/or MI rarely in patients w/ severe obstructive CAD. Concomitant use w/ SL nitroglycerin, long-acting nitrates, β-blockers or other anti-anginal agents. Hepatic impairment. May prolong labor duration. Pregnancy & lactation. Childn. Elderly.
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Adverse Reactions
Headache, edema, dizziness, flushing, palpitations; fatigue, nausea, abdominal pain, somnolence; muscle cramps, pruritus, rash.
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Drug Interactions
Additive hypotension w/ anesth & hydrocarbon inhalation; β-adrenergic blocking agents. Reduced antihypertensive effects w/ NSAIDs (indomethacin) & sympathomimetics. Increase BP due to induced fluid retention w/ estrogen. Changes in serum conc of free unbound medications w/ highly-protein bound medications (anticoagulants, coumarin & indandione derivatives, anticonvulsants, hydantoin, NSAIDs, quinine, salicylates, sulfinpyrazone). Potentiated antihypertensive effects w/ hypotension-producing medications. Neurotoxicity w/ lithium.
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Storage
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Action
View Vasalat mechanism of action for pharmacodynamics and pharmacokinetics details.
MIMS Class
Calcium Antagonists / Anti-Anginal Drugs
ATC Classification
C08CA01 - amlodipine ; Belongs to the class of dihydropyridine derivative selective calcium-channel blockers with mainly vascular effects. Used in the treatment of cardiovascular diseases.
Presentation/Packing
Form
Vasalat tab 10 mg
Packing/Price
100's (P1,969.8/pack);30's (P590.96/pack)
Form
Vasalat tab 5 mg
Packing/Price
100's (P1,195.9/pack);30's (P358.8/pack)
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