Vaneular

Vaneular

Manufacturer:

UNILAB, Inc

Distributor:

UNILAB, Inc
Full Prescribing Info
Contents
Vitamin B-complex.
Description
Each Tablet Contains: Thiamine Mononitrate (Vitamin B1) 300 mg, Riboflavin (Vitamin B2) 30 mg, Nicotinic Acid (Vitamin B3) 25 mg, Pyridoxine Hydrochloride (Vitamin B6) 100 mg, Cyanocobalamin (Vitamin B12) 250 mcg.
Vaneular contains B-complex vitamins (vitamins B1, B2, B6, B12 and Nicotinic Acid). These nutrients are required for the normal function of the nervous system and are used as adjunct in the management of various neuromuscular disorders.
B-complex vitamins also help in the conversion of food to energy to support numerous normal body processes.
B-complex vitamins have the following known functions/effects: See table.

Click on icon to see table/diagram/image
Indications/Uses
To treat deficiencies of vitamins B1, B2, B6, B12, and Nicotinic Acid manifested as: Muscle pain, loss of reflexes in the hands, knees, ankles, calves and feet and abnormal touch sensation such as burning and pricking.
As an adjunct in the management of conditions responsive to high dose vitamins B1, B2, B6, B12, and Nicotinic Acid which include the following: Neuralgia (nerve pain).
Neuritis (inflammation of the nerves).
Neuropathies (disturbances in the function of the brain or spinal cord that may affect the nerves and muscles of the body).
Inherited metabolic disorders such as: Leigh's necrotizing encephalopathy (a rare neurometabolic disorder characterized by degeneration or gradual loss of ability of the central nervous system, which includes the brain, spinal cord, and optic nerve, to function properly); Inherited vitamin B6 dependency; Methylmalonic aciduria (the accumulation of methylmalonic acid in the body characterized by progressive encephalopathy (brain disease that gets worse), dehydration, developmental delays, constipation, seizures and vomiting).
Lactic acidosis (a disease caused by the build-up of lactic acid in the body characterized by deep and rapid breathing, vomiting, and abdominal pain).
Wernicke's encephalopathy (an alcohol-induced thiamine deficiency characterized by mental confusion, staggering, and constant rapid eye movements).
Beri-beri (thiamine deficiency manifested as muscle weakness, loss of appetite, nerve degeneration (inability of nerves to function properly).
Use of drugs such as isoniazid, cycloserine, penicillamine, hydralazine and levodopa which induces increased requirement for vitamin B6.
Malabsorption syndromes.
Dosage/Direction for Use
Orally, one tablet daily. Or, as directed by a doctor.
If the patient misses a dose, just take the next dose and the subsequent doses at the usual recommended schedule, i.e., once a day. Do not double the dose.
Overdosage
Vitamin B6: Although vitamin B6 has generally been considered relatively nontoxic, long term (two months or longer) administration of large (megadose) dosages (usually 2 grams or more daily) of vitamin B6 can cause neurological symptoms manifested as paresthesia (more noticeable at night and limited to the extremities), bone pains (described as lightning, stabbing or shooting like a knitting needle or electric shocks), hyperesthesia (described as burning, pricking, stinging, or itching), muscle weakness (difficulty in running, lifting, climbing stairs and loss of manual dexterity), fasciculation (described as twitching, restlessness or fidgeting), and numbness of the limbs and face.
Nicotinic Acid: High-doses of Nicotinic Acid equivalent to 1.5 grams daily may cause dizziness, palpitations, shortness of breath, sweating, insomnia, nausea, vomiting, abdominal pain, and myalgia (muscle pain).
If the patient has taken more than the recommended dosage, consult a doctor or contact a Poison Control Center right away.
Contraindications
If the patient is allergic to any component of the product.
Special Precautions
Do not use more than the recommended dose.
Consult the doctor if symptoms persist or new symptoms appear.
Adverse Reactions
Pyridoxine (Vitamin B6): Undesirable neurologic effects have been reported after chronic administration of 500 mg vitamin B6 daily.
Nicotinic Acid: Dosages of Nicotinic Acid in excess of 100 mg daily may cause flushing of the face, arms, and chest, itching, and nausea.
Consult the doctor if any undesirable effect occurs.
Drug Interactions
Neuromuscular blocking agents (e.g., tubocurarine chloride, metocurine iodide, pancuronium bromide, and vecuronium bromide) may be enhanced by high doses of vitamin B1 (>500 mg daily), although the clinical significance of this is unknown.
Take this medicine (Vaneular) at least two hours before or after taking phenobarbital or phenytoin since high doses of vitamin B6 may reduce the blood levels of these drugs.
Storage
Store at temperatures not exceeding 30°C.
MIMS Class
Vitamin B-Complex / with C
ATC Classification
A11EA - Vitamin B-complex, plain ; Used as dietary supplements.
Presentation/Packing
Form
Vaneular tab
Packing/Price
100's (P21.92/tab, P2,192.25/pack)
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