Adult Herpes zoster 1,000 mg tid for 7 days.
Treatment of herpes simplex infections Immunocompetent adult & adolescent ≥12 yr 500 mg bid. Duration of therapy: Recurrent episodes: 3-5 days; initial episodes: 5-10 days.
Treatment of herpes labialis 2 g bid for 1 day; 2nd dose given 12 hr (not <6 hr) after 1st dose.
Prevention of recurrences of herpes simplex infections Given during prodromal period or at 1st signs & symptoms of recurrence.
Immunocompetent adult & adolescent ≥12 yr 500 mg once daily.
≥10 recurrences/yr 500 mg daily in divided doses (250 mg bid).
Immunocompromised patient 500 mg bid.
Reduction of transmission of genital herpes Immunocompetent heterosexual adult w/ ≤9 recurrences/yr 500 mg once daily given to infected partner.
Prophylaxis of CMV infection & disease 2 g qid as early as post-transplantation for 90 days.
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