Hypersensitivity. Hyperthyroidism, peptic ulcer, latent or active bronchial asthma, pronounced bradycardia or hypotension, vasomotor instability, CAD, epilepsy & parkinsonism; recent urinary bladder surgery, GI resection & anastomosis; bladder & GI obstruction or acute inflammatory lesions of the GIT, spastic GI disturbances, peritonitis; marked vagotonia.