Not intended in the treatment of pernicious anemia & other megaloblastic anemias where vit B
12 is deficient. Patients afflicted w/ pernicious anemia may not respond to orally administered vit B
12 w/ intrinsic factor conc. Periodic exam & lab studies of pernicious anemia is recommended. Discontinue or temporarily stop if intolerance occur. Folic acid in doses >0.1 mg daily. Doses >10 mcg of cyanocobalamin (vit B
12) in patients w/ folate deficiency; indiscriminate use may mask the precise diagnosis.