Trigenna Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Warnings Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Cefuroxime axetil

Indications/Uses

Treatment of infections due to sensitive gm +ve & gm -ve bacteria, surgical prophylaxis & more active against H. influenzae & Neisseria gonorrhoeae.

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Dosage/Direction for Use

Adult & adolescent ≥13 yr Pharyngitis/tonsillitis, acute bacterial maxillary sinusitis 250 mg bid for 10 days. Uncomplicated UTI & skin & skin structure infections 250 mg bid for 7-10 days. Acute bacterial exacerbations of chronic bronchitis 250 or 500 mg bid for 10 days. Secondary bacterial infection of acute bronchitis 250 or 500 mg bid for 5-10 days. Early lyme disease 500 mg bid for 20 days. Uncomplicated gonorrhea 1,000 mg once w/ single dose probenecid 1,000 mg. Childn Acute otitis media & bacterial maxillary sinusitis 250 mg bid for 10 days.

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Overdosage

View Trigenna overdosage for action to be taken in the event of an overdose.

Administration

Should be taken with food: Take w/ or after meals.

Contraindications

Hypersensitivity to cephalosporins.

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Warnings

For additional cautionary notes to warn of the potential risk of using the medicine... Click to view Trigenna detailed prescribing information

Special Precautions

Clostridium difficile-associated diarrhea. History of colitis; concurrent treatment w/ potent diuretics; renal or hepatic impairment of poor nutritional state, patients receiving protracted course of antimicrobial therapy & previously stabilized on anticoagulant therapy. Monitor prothrombin time in patients at risk. Pregnancy & lactation.

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Use In Pregnancy & Lactation

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Adverse Reactions

Hypersensitivity reactions: Anaphylaxis, angioedema, pruritus, rash, serum sickness-like reaction, urticaria, pseudomembranous colitis, hemolytic anemia, leukopenia, pancytopenia, thrombocytopenia, increased prothrombin time, hepatic impairment including hepatitis & cholestasis, jaundice, seizure, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, renal dysfunction.

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Drug Interactions

Probenecid; antacids; combined estrogen/progesterone OCs.

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Storage

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Description

View Trigenna description for details of the chemical structure and excipients (inactive components).

Action

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MIMS Class

Cephalosporins

ATC Classification

J01DC02 - cefuroxime ; Belongs to the class of second-generation cephalosporins. Used in the systemic treatment of infections.

Regulatory Classification

Presentation/Packing

Form

Trigenna tab 500 mg

Packing/Price

(Compliance pack) 14's (P730/box, P64/tab);100's (P64/tab, P6,400/box)

Trigenna

cefuroxime

Manufacturer:

Interphil

Distributor:

Interphil