Mixed hypercholesterolemia, hypertriglyceridemia, correction of low HDL in adult & dyslipidemia associated w/ metabolic syndrome & diabetes when the response to diet & lifestyle modification is inadequate.
View Triden overdosage for action to be taken in the event of an overdose.
Administration
Should be taken with food.
Contraindications
Hypersensitivity. Protoallergy or phototoxic reaction during treatment w/ fibrates or ketoprofen. Pre-existing gallbladder disease. Hepatic insufficiency (including biliary cirrhosis & unexplained persistent liver function abnormality); severe CKD; chronic or acute pancreatitis w/ exception of acute pancreatitis due to severe hypertriglyceridemia.
Secondary causes of hyperlipidemia (eg, uncontrolled type 2 DM, hypothyroidism, nephrotic syndrome, dysproteinemia, obstructive liver disease or alcoholism) should be treated prior to therapy. Pancreatitis, muscle toxicity. Increased risk of developing rhabdomyolysis in patients w/ pre-disposing factor for myopathy &/ rhabdomyolysis. Close monitoring of potential muscle toxicity. Monitor transaminase levels every 3 mth during the 1st 12 mth of therapy & thereafter periodically. Measure creatinine during the 1st 3 mth after initiation treatment & thereafter periodically. Pregnancy & lactation. Childn <18 yr.
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