Reduces of LDL-cholesterol, apolipoprotein B & triglycerides & increase HDL-cholesterol in the management of hyperlipidaemias, including primary hypercholesterolaemia (type IIa), mixed dyslipidaemia (type IIb), & hypertriglyceridaemia (type IV), as well as in patients w/ homozygous familial hypercholesterolaemia. Reduces the progression of atherosclerosis.