25 or 50 mg once daily. Increase dose up to 100 mg once daily in 1 or 2 divided doses for additional effects. Elderly >75 yr 25 mg once daily. Moderate to severe renal impairment (ie, CrCl <20 mL/min) or patients on dialysis25 mg once daily. Intravascular vol depletionUse a lower starting dose.
Symptomatic hypotension in patients who are intravascularly vol depleted (eg, those treated w/ high-dose diuretics). Patients w/ bilateral renal artery stenosis or stenosis of the artery to a solitary kidney. Hepatic impairment. Lactation. Childn.
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