IM 2 inj w/ an interval of 2 mth, 1 at the age of 2 mth & 1 at the age 4 mth, followed by 1 booster inj at the age of 11 mth, then another booster inj at the age of 6 yr, or, 3 inj at an interval of 1-2 mth from the age of 2 mth, followed by 1 booster inj 1 yr after primary vaccination ie, w/in the 2nd yr of life & another booster inj between 5 & 13 yr of age.
Hypersensitivity to glutaraldehyde, neomycin, streptomycin & polymixin B or to pertussis vaccines (acellular or whole cell). Evolving encephalopathy or encephalopathy w/in 7 days of a previous dose of pertussis vaccine. Postpone vaccination in case of febrile or acute disease.
Concomitant use w/ corticosteroids, cytotoxic drugs, radiotherapy or other drugs that may weaken the immune system. Guillain-Barre syndrome or brachial neuritis. Blood disoders eg, thrombocytopenia or clotting disorders. Fever ≥40°C, collapse or shock-like state w/ hypotonic-hyporesponsive episode, persistent, inconsolable crying lasting ≥3 hr w/in 48 hr vaccination; convulsions (w/ or w/o fever) w/in 3 days of vaccination. Edematous reactions of the lower limbs after inj of H. influenzae type b.
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