Management of hyperthyroidism including treatment of Grave's disease; prep of hyperthyroid patients for thyroidectomy. Adjunct to radio-iodine therapy & treatment of thyroid storm.
Patients should undergo close surveillance & monitored for mouth ulcers, sore throat, fever, bruising & malaise. May cause fetal harm when administered in the 1st trimester of pregnancy. Should not be given during pregnancy & lactation. Scalp defects, choanal, esophageal atresia & tracheoesophageal fistula in exposed infants. Monitor neonatal development & thyroid function closely in infants.
May potentiate activity of anticoagulants. Increased clearance of β blockers. Increased serum levels or digitalis glycosides. Decrease theophylline clearance.
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