Liver transplantation Initially 0.10-0.15 mg/kg/day every 12 hr in 2 divided doses. Administer initial dose no sooner than 6 hr after transplantation. If receiving IV infusion, 1st dose of oral therapy should be given 8-12 hr after discontinuing IV infusion.
Kidney transplantation Initially 0.2 mg/kg/day in combination w/ azathioprine or 0.1 mg/kg/day in combination w/ MMF & IL-2 receptor antagonist. May administer w/in 24 hr of transplantation. Delay until renal function has recovered.
Patient w/ heart transplantation Initially 0.075 mg/kg/day every 12 hr in 2 divided doses. Administer initial dose no sooner than 6 hr after transplantation. If receiving IV infusion, 1st dose of oral therapy should be given 8-12 hr after discontinuing IV infusion.
Childn Initially 0.15-0.20 mg/kg/day.
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