It is contraindicated in patients with pre-existing CNS depression or coma, bone marrow suppression, or phaeochromocytoma. It should not be used in patients with impaired liver, kidney, cardiovascular, cerebrovascular and respiratory function and in those with closed-angle glaucoma, Parkinsonism, diabetes mellitus, hypothyroidism, myasthenia gravis or prostatic hypertrophy. Because of its sedative effect, patients should not drive or operate machinery.
Also contraindicated in patients with suspected or established subcortical damage.
Hypersensitive to fluphenazine: Caution should observed in patients with a history of sensitivity to other phenothiazines, as across sensitivity may occur.